Where Are We in the Quest for Coronavirus Treatments?

• Antibody therapies: These contain producing antibodies in a lab that may be safely administered to sufferers to imitate the physique’s immune defenses to the coronavirus. U.S. regulators licensed two antibody therapies in November — REGEN-COV from Regeneron Prescription drugs Inc. and bamlanivimab from Eli Lilly & Co. — and a 3rd in Might known as sotrovimab from GlaxoSmithKline Plc and Vir Biotechnology Inc. All three had been cleared to be used towards mild-to-moderate Covid with a purpose of stopping instances from worsening to the purpose the place sufferers are hospitalized or die. In April, nevertheless, the Meals and Drug Administration revoked the authorization for solo use of bamlanivimab resulting from fears of decreased effectiveness towards coronavirus variants, and the U.S. authorities canceled a deal for hundreds of doses. In June, the federal government halted shipments of Lilly’s mixture of bamlanivimab and one other antibody, etesevimab, due to related considerations about effectiveness. Outcomes for REGEN-COV and sotrovimab, to date, have been extra promising. REGEN-COV decreased dying and hospitalization in high-risk sufferers by roughly 70%, in line with knowledge from a significant examine launched in April forward of evaluation by consultants uninvolved within the analysis. In July, the FDA licensed its use preventively in high-risk sufferers who’ve been uncovered to Covid or dwell in high-risk settings like nursing houses. In June, ultimate outcomes of the scientific trial for Glaxo’s sotrovimab instructed it decreased deaths and hospitalizations by 79%. None of those therapies is cleared to be used in severely unwell sufferers, nevertheless.

https://www.washingtonpost.com/enterprise/where-are-we-in-the-quest-forcoronavirustreatments/2021/08/16/ff2de176-fed4-11eb-87e0-7e07bd9ce270_story.html?utm_source=rss&utm_medium=referral&utm_campaign=wp_business | The place Are We within the Quest for Coronavirus Therapies?


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