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Smell tests can screen for COVID; Cancer patients need both Pfizer doses

By Nancy Lapid

(Reuters) – Here’s a roundup of among the newest scientific research on the novel coronavirus and efforts to seek out therapies and vaccines for COVID-19, the sickness attributable to the virus.

Odor take a look at would possibly enhance COVID-19 screening

A “odor take a look at” is perhaps a greater approach to display for the novel coronavirus than checking for cough or fever, a brand new examine suggests. COVID-19 sufferers typically lose their sense of odor with out realizing it, however researchers had been in a position to make use of easy scratch-and-sniff playing cards to appropriately determine 75% of contaminated people and 95% of individuals with out the illness. Within the examine, 163 adults – who had been being screened for COVID-19 with gold-standard PCR evaluation of nasal swabs – had been every given a card with scratch-and-sniff scents that they needed to determine from a multiple-choice choice. “In comparison with different signs like cough, fever, fatigue, and historical past of COVID-19 publicity, failing the odor card was the very best predictor of COVID-19 positivity,” Dr. Mena Mentioned of the College of California, San Diego instructed Reuters. Fast odor assessments is perhaps a sensible approach to cut back COVID-19 transmission, he added, if bigger research with extra various populations verify these findings, which had been reported on Thursday in JAMA Otolaryngology – Head and Neck Surgical procedure https://bit.ly/3etefKV.

Good vaccine responses seen in sufferers with stable tumors

The Pfizer-BioNTech COVID-19 vaccine seems to work nicely in sufferers receiving most cancers therapies, in response to a examine from Israel. Whereas there was a “pronounced” lag in antibody manufacturing within the most cancers sufferers in contrast with non-cancer examine topics, most sufferers caught up after the second dose, researchers reported in JAMA Oncology https://bit.ly/3hqTIbB. They studied 232 sufferers with stable tumors receiving varied therapies – akin to chemotherapy, organic brokers, or immunotherapy, or some mixture – and 261 wholesome folks of comparable ages. After the primary dose of vaccine, 29% of most cancers sufferers had been producing antibodies, in contrast with 84% of controls. However after the second dose, most cancers sufferers’ price reached 86%. Unwanted side effects had been just like these in trials of wholesome people, and not one of the most cancers sufferers has developed a case of COVID-19, the researchers stated. They added that most cancers sufferers’ second dose must be given in response to the schedule beneficial by the producer, even in areas the place the standard coverage is to delay the second dose attributable to vaccine shortages.

COVID-19 problems impair life after hospital discharge

Almost 50% of adults hospitalized with COVID-19 develop problems, and infrequently these issues have an effect on their means to look after themselves after discharge, new analysis signifies. Males and people older than 50 had been almost certainly to develop problems, however youthful, beforehand wholesome adults weren’t spared, researchers reported on Thursday in The Lancet https://bit.ly/3ikvgbi. “This work contradicts present narratives that COVID-19 is simply harmful in folks with current comorbidities and the aged,” coauthor Dr. Calum Semple of the College of Liverpool stated in a information launch. His group studied 73,197 adults hospitalized with COVID-19 throughout the UK in 2020. Total, 49.7% suffered at the very least one complication, affecting the kidneys in 24%, inhaling 18%, a number of organs in 16%, the guts in 12%, the gastrointestinal system in 11%, and the nervous system in 4%. Issues occurred in 39% of people ages 19 to 49, in comparison with 51% of these over age 50. Charges had been highest in Black sufferers. After leaving the hospital, a couple of in 4 sufferers had been much less capable of look after themselves than earlier than they received sick. “Simply specializing in dying from COVID-19 is prone to underestimate the true affect, notably in youthful people who find themselves extra prone to survive extreme COVID-19,” coauthor Dr. Aya Riad of the College of Edinburgh stated within the information launch.

Emergency departments seeing extra mask-related accidents

The spike in face masks use in the course of the pandemic got here with a spike in mask-related accidents, a brand new examine reveals. From 2016 by means of 2019, a median of 200 such accidents had been handled yearly in U.S. emergency departments. In 2020, that quantity went up by 2,400%, to almost 5,000, in response to information printed on Friday. The accidents occurred in any respect ages, with white and Black folks equally represented, researchers reported within the Journal of the American Academy of Dermatology https://bit.ly/3et6xjP. Commonest had been pores and skin irritation, rashes, and allergic reactions. However 14% of mask-related accidents had been attributable to obscured imaginative and prescient and included falls and motorcar accidents. 5 p.c had been in youngsters who had eaten a chunk of a masks or caught a chunk into the nostril or different orifice. Three p.c of accidents, all in aged folks, had been attributable to falls from bending over to choose up a dropped masks. “The Facilities for Illness Management and Prevention has printed suggestions and assets https://bit.ly/3ep67uE to assist within the alternative and correct match of face masks,” the examine authors wrote. “The outcomes of the present examine underscore the necessity for elevated consciousness of those assets with a purpose to reduce the longer term incidence of mask-related accidents.”

Click on for a Reuters graphic https://tmsnrt.rs/3c7R3Bl on vaccines in improvement.

(Reporting by Nancy Lapid and Megan Brooks; Enhancing by Tiffany Wu)

Smell tests can screen for COVID; Cancer patients need both Pfizer doses

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