NFL odds, lines, picks, predictions for Week 1, 2021: Top-rated model backing 49ers, Panthers

Two of probably the most thrilling NFL quarterbacks might be on full show Sunday when Patrick Mahomes and the Kansas Metropolis Chiefs host Baker Mayfield and the Cleveland Browns. The Chiefs secured a 22-17 victory over the Browns at Arrowhead Stadium within the AFC Divisional Spherical final season. The newest Week 1 NFL odds from Caesars Sportsbook record Kansas Metropolis as a six-point residence favourite.

There are additionally cross-divisional battles in Week 1 of the 2021 NFL schedule, together with Seahawks vs. Colts, Chargers vs. Washington and Broncos vs. Giants. The Seahawks are 2.5-point highway favorites, whereas the Giants are three-point residence underdogs in keeping with the Week 1 NFL spreads. The entire Week 1 NFL strains are listed beneath, and SportsLine’s advanced computer model has all the NFL betting advice and predictions you need to make the best Week 1 NFL picks now

The mannequin, which simulates each NFL recreation 10,000 occasions, is up virtually $7,900 for $100 gamers on top-rated NFL picks since its inception six years in the past. It went a scorching 24-14 on top-rated NFL picks final season, returning greater than $800. The mannequin additionally enters the 2021 season on an unbelievable 120-78 run on top-rated NFL picks that dates again to the 2017 season.

The mannequin additionally ranked within the High 10 on NFLPickWatch 4 of the previous 5 years on straight-up NFL picks and beat greater than 94 % of CBS Sports activities Soccer Choose’em gamers 4 occasions throughout that span. Anybody who has adopted it’s means up.

Now, it has turned its consideration to the most recent Week 1 NFL odds from Caesars and locked in picks for each NFL matchup. Head here to see every pick.

High Week 1 NFL predictions

One of many high Week 1 NFL predictions the mannequin recommends: The 49ers (-7.5) cowl the unfold in opposition to the Lions. The 49ers and Lions had been solely separated by a recreation within the NFC standings a season in the past, however a fast look at their rosters makes it fairly clear that they are much additional aside than the information may point out.

The 49ers may have Jimmy Garoppolo, Raheem Mostert, Deebo Samuel, George Kittle, Nick Bosa, Dee Ford and Jaquiski Tartt again of their Week 1 lineup after all of them hung out on injured reserve final season. In the meantime, the Lions took a step again in effort to rebuild their roster, swapping Matthew Stafford for Jared Goff.

The Lions additionally misplaced Kenny Golladay in free company, and the mannequin is predicting that the offense will wrestle transferring the soccer in opposition to a 49ers protection that ranked high 5 within the NFL in yards allowed regardless of all of the defensive accidents. Detroit is projected to realize fewer than 325 yards, whereas the 49ers’ offense will put up practically 450 yards of complete offense. San Francisco covers in over 50 % of simulations.

One other one of many high Week 1 NFL picks from the mannequin: The Panthers (-5.5) cowl as residence favorites in opposition to the Jets. This can be a revenge recreation for Panthers quarterback Sam Darnold, who spent his first three seasons with the Jets. Darnold will lead a Carolina offense that options Christian McCaffrey, D.J. Moore, Robby Anderson and Terrace Marshall.

McCaffrey grew to become simply the third player in NFL historical past with not less than 1,000 dashing yards and 1,000 receiving yards in the identical season in 2019. Carolina’s working again handled quite a few accidents in 2020, however he’ll be desperate to dominate a New York protection that gave up 387.6 yards per recreation final season.

SportsLine’s mannequin is anticipating McCaffrey to rack up practically 130 all-purpose yards in opposition to the Jets. The mannequin has additionally taken under consideration that the Panthers are 7-0 of their final seven video games in opposition to opponents from the AFC East.

Methods to make Week 1 NFL picks 

The mannequin has additionally made the decision on who wins and covers in each different recreation on the Week 1 NFL schedule, and it is calling for a Tremendous Bowl contender to go down laborious. You can only get every pick for every game at SportsLine.

So what NFL picks are you able to make with confidence? And which Tremendous Bowl contender goes down laborious? Take a look at the most recent NFL odds beneath, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned almost $7,900 since its inception, and discover out.

Week 1 NFL odds (by way of Caesars)

Thursday, Sept. 9 

Cowboys at Buccaneers (-8, 51.5)

Featured Recreation | Tampa Bay Buccaneers vs. Dallas Cowboys

Sunday, Sept. 12

Steelers at Bills (-6.5, 48.5)

Featured Recreation | Buffalo Payments vs. Pittsburgh Steelers

Jets at Panthers (-5.5, 44.5)

Featured Recreation | Carolina Panthers vs. New York Jets

Jaguars at Texans (+2.5, 44.5)

Featured Recreation | Houston Texans vs. Jacksonville Jaguars

Cardinals at Titans (-3. 52)

Featured Recreation | Tennessee Titans vs. Arizona Cardinals

Chargers at Washington (+1, 44.5)

Featured Recreation | Washington Soccer Staff vs. Los Angeles Chargers

Eagles at Falcons (-3, 48)

Featured Recreation | Atlanta Falcons vs. Philadelphia Eagles

Seahawks at Colts (+2.5, 49.5)

Featured Recreation | Indianapolis Colts vs. Seattle Seahawks

Vikings at Bengals (+3, 47.5)

Featured Recreation | Cincinnati Bengals vs. Minnesota Vikings

49ers at Lions (+7.5, 45)

Featured Recreation | Detroit Lions vs. San Francisco 49ers

Browns at Chiefs (-6, 54.5)

Featured Recreation | Kansas Metropolis Chiefs vs. Cleveland Browns

Dolphins at Patriots (-3, 43.5)

Featured Recreation | New England Patriots vs. Miami Dolphins

Broncos at Giants (+3, 42)

Featured Recreation | New York Giants vs. Denver Broncos

Packers at Saints (+4, 50)

Featured Recreation | New Orleans Saints vs. Inexperienced Bay Packers

Bears at Rams (-7.5, 46.5)

Featured Recreation | Los Angeles Rams vs. Chicago Bears

Monday, Sept. 13

Ravens at Raiders (+4.5, 50.5)

Featured Recreation | Las Vegas Raiders vs. Baltimore Ravens | NFL odds, strains, picks, predictions for Week 1, 2021: High-rated mannequin backing 49ers, Panthers


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