49ers vs. Chargers odds, picks, line: 2021 NFL preseason Week 2 predictions, best bets from expert on 14-6 run

After two days of intense joint practices, the San Francisco 49ers and Los Angeles Chargers will sq. off Sunday night time in a Week 2 NFL preseason matchup at SoFi Stadium. The groups have met 48 instances within the preseason, with San Francisco holding a 26-22 benefit. Each groups completed beneath .500 final season, with the injury-ravaged Niners following up an NFC championship season with a 6-10 mark. Los Angeles went 7-9 in its first season with out Philip Rivers at quarterback since 2005. San Francisco drafted Trey Lance to compete with incumbent quarterback Jimmy Garoppolo, whereas league Offensive Rookie of the 12 months Justin Herbert introduced hope to Los Angeles.

Kickoff is ready for 7:30 p.m. ET in Inglewood, Calif. San Francisco is listed as a 5.5-point favourite within the newest 49ers vs. Chargers odds from Caesars Sportsbook, whereas the over-under for whole factors scored is 34. Earlier than making any Chargers vs. 49ers picks, be sure you see the NFL predictions and betting advice from SportsLine’s Tom Fornelli

The CBS nationwide author went a worthwhile 31-22 final season on his NFL finest bets. What’s extra, he has demonstrated a very sharp eye for the 49ers. In actual fact, Fornelli has gone a surprising 14-6 on NFL picks involving San Francisco. Anybody who has adopted him is manner up.

Now, Hunt has set his sights on 49ers vs. Chargers and not too long ago revealed his skilled NFL picks and evaluation. You can head to SportsLine now to see his picks. Listed below are the NFL lines and betting tendencies for Chargers vs. 49ers:

  • 49ers vs. Chargers unfold: 49ers -5.5
  • 49ers vs. Chargers over-under: 34 factors
  • 49ers vs. Chargers cash line: 49ers -245, Chargers +205
  • SF: San Francisco was 3-0 in opposition to the unfold as a highway favourite in 2020
  • LAC: Los Angeles went 5-2 ATS as an underdog final season

Featured Recreation | Los Angeles Chargers vs. San Francisco 49ers

Why the 49ers can cowl

Lance’s presence will profit San Francisco within the preseason, with Garoppolo attempting to show himself once more after taking part in solely six video games in 2020. Garoppolo, who gained 17 of his first 20 profession begins, led the group to a 3-3 mark in these video games and threw seven TDs and 5 interceptions.

Lance gained all 17 school begins at North Dakota State and threw only one interception in his profession, however did not put up gaudy numbers and might want to acclimate to big-time competitors. The Niners put up 383 yards final week in a 19-16 loss to the Chiefs, with 175 on the bottom.

They’d 5 gamers who ran for at the least 20 yards, led by JaMycal Hasty, who put up 63 on simply 10 carries. Trey Sermon and Wayne Gallman are anticipated to be the backups to Raheem Mostert, so these fierce battles additionally ought to profit San Francisco. Receiver Nsimba Webster broke off a 34-yard run on his solely carry because the Niners outgained Kansas Metropolis by greater than 100 yards. They allowed 74 on the bottom and 258 whole, posting 4 sacks and forcing a turnover. 

Why the Chargers can cowl

The Chargers dominated the Rams final week, holding them underneath 200 whole yards and simply 3.6 per play. Now, they face a Niners offensive line that’s banged up, and the mixture of strain and San Francisco’s quarterbacks attempting to be aggressive to impress the teaching workers ought to profit the Chargers. San Francisco gave up 5 sacks and turned the ball over twice within the loss to the Chiefs, along with dropping 73 yards on penalties.

Lance was sacked 5 instances and threw an interception in Thursday’s follow, and the Niners’ offensive line struggled to open holes for the backs. The Chargers held the Rams to three.0 yards per carry in a 13-6 victory final week, so San Francisco has an uphill battle. Herbert shouldn’t be anticipated to play within the preseason, together with a number of key Chargers starters, so veteran backup Chase Daniel will begin. With the 49ers anticipated to relaxation a lot of their beginning protection, Los Angeles ought to be capable of exploit a secondary made up of NFL newcomers. Daniel and Easton Stick mixed to go 22-of-31 for 167 yards final week, and K.J. Costello may see motion.   

Tips on how to make Chargers vs. 49ers picks

Fornelli has analyzed this matchup from all angles, and he’s leaning underneath on the purpose whole. He additionally has found a crucial X-factor that has him leaping throughout one aspect of the unfold. He’s only sharing what it is and his expert Niners vs. Chargers picks at SportsLine.

So who wins Niners vs. Chargers? And which crucial X-factor makes one aspect of the unfold a must-back? Visit SportsLine now to see Tom Fornelli’s 49ers vs. Chargers pick, all from the NFL expert who’s 14-6 on picks involving San Francisco, and discover out. | 49ers vs. Chargers odds, picks, line: 2021 NFL preseason Week 2 predictions, finest bets from skilled on 14-6 run


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